The First Ever Blood Transfusions.
ROBERT BOYLE
The field of blood transfusion can rightly be said to have
started in the 1660s.On the 17th December 1666, Richard Lower an
Oxford physician published a paper
in the Philosophical Transactions which described an experiment in where the
procedure was carried out among dogs. The paper can be accessed from JSTOR. To be
more precise, he informed the famous Robert Boyle about his work and he
communicated this to the journal. Incidentally,
the Philosophical Transactions is the oldest continually published scientific journal
in the world. Incidentally, Aurangzeb still ruled India and
the Jantar Mantar was not to be built until more than 50 years later.
The description of the experiment would have all the animal
activists in the world up in arms. The carotid artery of the first dog was
exposed and tied off distally and the proximal part tied with a ligature that
could be loosened at will. A (goose?) quill was placed in this and this dog
acted as the donor. The recipient dog had his jugular vein exposed and two
quills were placed, one nearer the heart to receive the blood form the donor
and a second one to drain blood away from the dog. The bleeding continued until the first
dog began “ to cry, and faint, and fall
into Convulsions,and at last dye by his side”.
The recipient was, however made of sterner stuff. This dog ,
if you “sow up the skin and dismiss him and
the Dog will leap from the Table and shaken himself and run away as if nothing
ailed him “ Dr Lower planned to repeat this
experiment, not on one dog, but by
bleeding several dogs into one and even several creatures into one . However the
results of these experiments, if they were carried out are not known to us.
Boyle, in another paper published a few months later asked
some pertinent theoretical questions about the experiments. The particular date
of the issue in which he published his article is perhaps wrongly printed as February 11, 1666. Possibly it should be
1667.
Anyway, Boyle asked some important questions , 16 in number .
I think it would be nice to see the actual facsimile of the questions he asked extracted from the Philosophical Transactions.
Of first human transfusions, a later post.
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